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INFLAMMATION 31
CHAPTER IV
SUPPURATION 45
CHAPTER V
ULCERATION AND ULCERS 68
CHAPTER VI
GANGRENE 86
CHAPTER VII
BACTERIAL AND OTHER WOUND INFECTIONS 107
CHAPTER VIII
TUBERCULOSIS 133
CHAPTER IX
SYPHILIS 146
CHAPTER X
TUMOURS 181
CHAPTER XI
INJURIES 218
CHAPTER XII
METHODS OF WOUND TREATMENT 241
CHAPTER III 5
CHAPTER XIII
CONSTITUTIONAL EFFECTS OF INJURIES 249
CHAPTER XIV
THE BLOOD VESSELS 258
CHAPTER XV
THE LYMPH VESSELS AND GLANDS 321
CHAPTER XVI
THE NERVES 342
CHAPTER XVII
SKIN AND SUBCUTANEOUS TISSUES 376
CHAPTER XVIII
THE MUSCLES, TENDONS, AND TENDON SHEATHS 405
CHAPTER XIX
THE BURSÆ 426
CHAPTER XX
DISEASES OF BONE 434
CHAPTER XXI
DISEASES OF JOINTS 501
INDEX 547
LIST OF ILLUSTRATIONS
FIG. PAGE
CHAPTER XIII 6
1. Ulcer of Back of Hand grafted from Abdominal Wall 15
2. Staphylococcus aureus in Pus from case of Osteomyelitis 25
3. Streptococci in Pus from case of Diffuse Cellulitis 26
4. Bacillus coli communis in Pus from Abdominal Abscess 27
5. Fraenkel's Pneumococci in Pus from Empyema following 28 Pneumonia
6. Passive Hyperæmia of Hand and Forearm induced by Bier's 37 Bandage
7. Passive Hyperæmia of Finger induced by Klapp's Suction 38 Bell
8. Passive Hyperæmia induced by Klapp's Suction Bell for 39 Inflammation of Inguinal Gland
9. Diagram of various forms of Whitlow 56
10. Charts of Acute Sapræmia 61
11. Chart of Hectic Fever 62
12. Chart of Septicæmia followed by Pyæmia 63
13. Chart of Pyæmia following on Acute Osteomyelitis 65
14. Leg Ulcers associated with Varicose Veins 71
15. Perforating Ulcers of Sole of Foot 74
16. Bazin's Disease in a girl æt. 16 75
17. Syphilitic Ulcers in region of Knee 76
18. Callous Ulcer showing thickened edges 78
19. Tibia and Fibula, showing changes due to Chronic Ulcer of 80 Leg
20. Senile Gangrene of the Foot 89
21. Embolic Gangrene of Hand and Arm 92
22. Gangrene of Terminal Phalanx of Index-Finger 100
23. Cancrum Oris 103
24. Acute Bed Sores over right Buttock 104
25. Chart of Erysipelas occurring in a wound 108
26. Bacillus of Tetanus 113
CHAPTER XXI 7
27. Bacillus of Anthrax 120
28. Malignant Pustule third day after infection 122
29. Malignant Pustule fourteen days after infection 122
30. Colony of Actinomyces 126
31. Actinomycosis of Maxilla 128
32. Mycetoma, or Madura Foot 130
33. Tubercle bacilli 134
34. Tuberculous Abscess in Lumbar Region 141
35. Tuberculous Sinus injected through its opening in the 144 Forearm with Bismuth Paste
36. Spirochæte pallida 147
37. Spirochæta refrigerans from scraping of Vagina 148
38. Primary Lesion on Thumb, with Secondary Eruption on 154 Forearm
39. Syphilitic Rupia 159
40. Ulcerating Gumma of Lips 169
41. Ulceration in inherited Syphilis 170
42. Tertiary Syphilitic Ulceration in region of Knee and on 171 both Thumbs
43. Facies of Inherited Syphilis 174
44. Facies of Inherited Syphilis 175
45. Subcutaneous Lipoma 185
46. Pedunculated Lipoma of Buttock 186
47. Diffuse Lipomatosis of Neck 187
48. Zanthoma of Hands 188
49. Zanthoma of Buttock 189
50. Chondroma growing from Infra-Spinous Fossa of Scapula 190
51. Chondroma of Metacarpal Bone of Thumb 190
52. Cancellous Osteoma of Lower End of Femur 192
CHAPTER XXI 8
53. Myeloma of Shaft of Humerus 195
54. Fibro-myoma of Uterus 196
55. Recurrent Sarcoma of Sciatic Nerve 198
56. Sarcoma of Arm fungating 199
57. Carcinoma of Breast 206
58. Epithelioma of Lip 209
59. Dermoid Cyst of Ovary 213
60. Carpal Ganglion in a woman æt. 25 215
61. Ganglion on lateral aspect of Knee 216
62. Radiogram showing pellets embedded in Arm 228
63. Cicatricial Contraction following Severe Burn 236
64. Genealogical Tree of Hæmophilic Family 278
65. Radiogram showing calcareous degeneration of Arteries 284
66. Varicose Vein with Thrombosis 289
67. Extensive Varix of Internal Saphena System on Left Leg 291
68. Mixed Nævus of Nose 296
69. Cirsoid Aneurysm of Forehead 299
70. Cirsoid Aneurysm of Orbit and Face 300
71. Radiogram of Aneurysm of Aorta 303
72. Sacculated Aneurysm of Abdominal Aorta 304
73. Radiogram of Innominate Aneurysm after Treatment by 309 Moore-Corradi method
74. Thoracic Aneurysm threatening to rupture 313
75. Innominate Aneurysm in a woman 315
76. Congenital Cystic Tumour or Hygroma of Axilla 328
77. Tuberculous Cervical Gland with Abscess formation 331
78. Mass of Tuberculous Glands removed from Axilla 333
CHAPTER XXI 9
79. Tuberculous Axillary Glands 335
80. Chronic Hodgkin's Disease in boy æt. 11 337
81. Lymphadenoma in a woman æt. 44 338
82. Lympho Sarcoma removed from Groin 339
83. Cancerous Glands in Neck, secondary to Epithelioma of Lip 341
84. Stump Neuromas of Sciatic Nerve 345
85. Stump Neuromas, showing changes at ends of divided Nerves 354
86. Diffuse Enlargement of Nerves in generalised 356 Neuro-Fibromatosis
87. Plexiform Neuroma of small Sciatic Nerve 357
88. Multiple Neuro-Fibromas of Skin (Molluscum fibrosum) 358
89. Elephantiasis Neuromatosa in a woman æt. 28 359
90. Drop-Wrist following Fracture of Shaft of Humerus 365
91. To illustrate the Loss of Sensation produced by Division 367 of the Median Nerve
92. To illustrate Loss of Sensation produced by Complete 368 Division of Ulnar Nerve
93. Callosities and Corns on Sole of Foot 377
94. Ulcerated Chilblains on Fingers 378
95. Carbuncle on Back of Neck 381
96. Tuberculous Elephantiasis 383
97. Elephantiasis in a woman æt. 45 387
98. Elephantiasis of Penis and Scrotum 388
99. Multiple Sebaceous Cysts or Wens 390
100. Sebaceous Horn growing from Auricle 392
101. Paraffin Epithelioma 394
102. Rodent Cancer of Inner Canthus 395
103. Rodent Cancer with destruction of contents of Orbit 396
104. Diffuse Melanotic Cancer of Lymphatics of Skin 398
CHAPTER XXI 10
105. Melanotic Cancer of Forehead with Metastasis in Lymph 399 Glands
106. Recurrent Keloid 401
107. Subungual Exostosis 403
108. Avulsion of Tendon 410
109. Volkmann's Ischæmic Contracture 414
110. Ossification in Tendon of Ilio-psoas Muscle 417
111. Radiogram of Calcification and Ossification in Biceps and 418 Triceps
112. Ossification in Muscles of Trunk in generalised Ossifying 419 Myositis
113. Hydrops of Prepatellar Bursa 427
114. Section through Gouty Bursa 428
115. Tuberculous Disease of Sub-Deltoid Bursa 429
116. Great Enlargement of the Ischial Bursa 431
117. Gouty Disease of Bursæ 432
118. Shaft of the Femur after Acute Osteomyelitis 444
119. Femur and Tibia showing results of Acute Osteomyelitis 445
120. Segment of Tibia resected for Brodie's Abscess 449
121. Radiogram of Brodie's Abscess in Lower End of Tibia 451
122. Sequestrum of Femur after Amputation 453
123. New Periosteal Bone on Surface of Femur from Amputation 454 Stump
124. Tuberculous Osteomyelitis of Os Magnum 456
125. Tuberculous Disease of Tibia 457
126. Diffuse Tuberculous Osteomyelitis of Right Tibia 458
127. Advanced Tuberculous Disease in Region of Ankle 459
128. Tuberculous Dactylitis 460
129. Shortening of Middle Finger of Adult, the result of 461 Tuberculous Dactylitis in Childhood
130. Syphilitic Disease of Skull 463
CHAPTER XXI 11
131. Syphilitic Hyperostosis and Sclerosis of Tibia 464
132. Sabre-blade Deformity of Tibia 467
133. Skeleton of Rickety Dwarf 470
134. Changes in the Skull resulting from Ostitis Deformans 474
135. Cadaver, illustrating the alterations in the Lower Limbs 475 resulting from Ostitis Deformans
136. Osteomyelitis Fibrosa affecting Femora 476
137. Radiogram of Upper End of Femur in Osteomyelitis Fibrosa 478
138. Radiogram of Right Knee showing Multiple Exostoses 482
139. Multiple Exostoses of Limbs 483
140. Multiple Cartilaginous Exostoses 484
141. Multiple Cartilaginous Exostoses 486
142. Multiple Chondromas of Phalanges and Metacarpals 488
143. Skiagram of Multiple Chondromas 489
144. Multiple Chondromas in Hand 490
145. Radiogram of Myeloma of Humerus 492
146. Periosteal Sarcoma of Femur 493
147. Periosteal Sarcoma of Humerus 493
148. Chondro-Sarcoma of Scapula 494
149. Central Sarcoma of Femur invading Knee Joint 495
150. Osseous Shell of Osteo-Sarcoma of Femur 495
151. Radiogram of Osteo-Sarcoma of Femur 496
152. Radiogram of Chondro-Sarcoma of Humerus 497
153. Epitheliomatus Ulcer of Leg invading Tibia 499
154. Osseous Ankylosis of Femur and Tibia 503
155. Osseous Ankylosis of Knee 504
156. Caseating focus in Upper End of Fibula 513
CHAPTER XXI 12
157. Arthritis Deformans of Elbow 525
158. Arthritis Deformans of Knee 526
159. Hypertrophied Fringes of Synovial Membrane of Knee 527
160. Arthritis Deformans of Hands 529
161. Arthritis Deformans of several Joints 530
162. Bones of Knee in Charcot's Disease 533
163. Charcot's Disease of Left Knee 534
164. Charcot's Disease of both Ankles: front view 535
165. Charcot's Disease of both Ankles: back view 536
166. Radiogram of Multiple Loose Bodies in Knee-joint 540
167. Loose Body from Knee-joint 541
168. Multiple partially ossified Chondromas of Synovial 542 Membrane from Shoulder-joint
169. Multiple Cartilaginous Loose Bodies from Knee-joint 543
MANUAL OF SURGERY
CHAPTER I
REPAIR
Introduction Process of repair Healing by primary union Granulation tissue Cicatricial
tissue Modifications of process of repair Repair in individual tissues Transplantation or grafting of
tissues Conditions Sources of grafts Grafting of individual tissues Methods.
INTRODUCTION
To prolong human life and to alleviate suffering are the ultimate objects of scientific medicine. The two great
branches of the healing art Medicine and Surgery are so intimately related that it is impossible to draw a
hard-and-fast line between them, but for convenience Surgery may be defined as "the art of treating lesions
and malformations of the human body by manual operations, mediate and immediate." To apply his art
intelligently and successfully, it is essential that the surgeon should be conversant not only with the normal
anatomy and physiology of the body and with the various pathological conditions to which it is liable, but also
with the nature of the process by which repair of injured or diseased tissues is effected. Without this
knowledge he is unable to recognise such deviations from the normal as result from mal-development, injury,
or disease, or rationally to direct his efforts towards the correction or removal of these.
PROCESS OF REPAIR
CHAPTER I 13
The process of repair in living tissue depends upon an inherent power possessed by vital cells of reacting to
the irritation caused by injury or disease. The cells of the damaged tissues, under the influence of this
irritation, undergo certain proliferative changes, which are designed to restore the normal structure and
configuration of the part. The process by which this restoration is effected is essentially the same in all tissues,
but the extent to which different tissues can carry the recuperative process varies. Simple structures, such as
skin, cartilage, bone, periosteum, and tendon, for example, have a high power of regeneration, and in them the
reparative process may result in almost perfect restitution to the normal. More complex structures, on the
other hand, such as secreting glands, muscle, and the tissues of the central nervous system, are but imperfectly
restored, simple cicatricial connective tissue taking the place of what has been lost or destroyed. Any given
tissue can be replaced only by tissue of a similar kind, and in a damaged part each element takes its share in
the reparative process by producing new material which approximates more or less closely to the normal
according to the recuperative capacity of the particular tissue. The normal process of repair may be interfered
with by various extraneous agencies, the most important of which are infection by disease-producing
micro-organisms, the presence of foreign substances, undue movement of the affected part, and improper
applications and dressings. The effect of these agencies is to delay repair or to prevent the individual tissues
carrying the process to the furthest degree of which they are capable.
In the management of wounds and other diseased conditions the main object of the surgeon is to promote the
natural reparative process by preventing or eliminating any factor by which it may be disturbed.
#Healing by Primary Union.# The most favourable conditions for the progress of the reparative process are
to be found in a clean-cut wound of the integument, which is uncomplicated by loss of tissue, by the presence
of foreign substances, or by infection with disease-producing micro-organisms, and its edges are in contact.
Such a wound in virtue of the absence of infection is said to be aseptic, and under these conditions healing
takes place by what is called "primary union" the "healing by first intention" of the older writers.
#Granulation Tissue.# The essential and invariable medium of repair in all structures is an elementary form
of new tissue known as _granulation tissue_, which is produced in the damaged area in response to the
irritation caused by injury or disease. The vital reaction induced by such irritation results in dilatation of the
vessels of the part, emigration of leucocytes, transudation of lymph, and certain proliferative changes in the
fixed tissue cells. These changes are common to the processes of inflammation and repair; no hard-and-fast
line can be drawn between these processes, and the two may go on together. It is, however, only when the
proliferative changes have come to predominate that the reparative process is effectively established by the
production of healthy granulation tissue.
Formation of Granulation Tissue When a wound is made in the integument under aseptic conditions, the
passage of the knife through the tissues is immediately followed by an oozing of blood, which soon
coagulates on the cut surfaces. In each of the divided vessels a clot forms, and extends as far as the nearest
collateral branch; and on the surface of the wound there is a microscopic layer of bruised and devitalised
tissue. If the wound is closed, the narrow space between its edges is occupied by blood-clot, which consists of
red and white corpuscles mixed with a quantity of fibrin, and this forms a temporary uniting medium between
the divided surfaces. During the first twelve hours, the minute vessels in the vicinity of the wound dilate, and
from them lymph exudes and leucocytes migrate into the tissues. In from twenty-four to thirty-six hours, the
capillaries of the part adjacent to the wound begin to throw out minute buds and fine processes, which bridge
the gap and form a firmer, but still temporary, connection between the two sides. Each bud begins in the wall
of the capillary as a small accumulation of granular protoplasm, which gradually elongates into a filament
containing a nucleus. This filament either joins with a neighbouring capillary or with a similar filament, and in
time these become hollow and are filled with blood from the vessels that gave them origin. In this way a series
of young capillary loops is formed.
The spaces between these loops are filled by cells of various kinds, the most important being the fibroblasts,
which are destined to form cicatricial fibrous tissue. These fibroblasts are large irregular nucleated cells
CHAPTER I 14
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